The use of neuropeptides (memoprove™) in geriatric pharmacology
Abstract
The article presents our own data on the effect of the MemoProve™ course of treatment (1 tablet for 30 days) in 20 elderly researchers (mean age 68.2+3.2 years) on mnestic processes (short-term, long-term memory), emotional background (anxiety level); besides, the article presents a structural characteristic of the reorganisation of the brain bioelectrical activity and changes in cerebral haemodynamics. Three types of EEG response to MemoProve™ have been identified. Common to these types is an increase in the total power of brain electrogenesis (by 15-25%) and an increase in the frequency of the arhythm, the main, basic EEG rhythm. The type of influence of MemoProve™ on the power of slow rhythms (delta, theta) depends on the EEG type.
In elderly patients, MemoProve™ caused an increase in the Linear Systolic Blood Flow (LSBF) rate in the two middle cerebral arteries (MCAs), vertebral arteries (VAs) and basilar artery (BA). The results of a comprehensive analysis of the impact of the MemoProve™ course of treatment testify to its positive effect on the brain functional state (according to emotional-mnestic parameters, brain bioelectrical activity, cerebral haemodynamics) in the elderly and give reason to recommend MemoProve™ for use in the geriatric pharmacological correction of emotional-mnestic activity.
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