Melatoninergic antidepressants in the treatment of post-stroke depression
Abstract
Abstact. The article presents data about the impact of the drug Melitor (agomelatine) on the psycho-emotional activity, cerebral hemodynamics, bioelectric activity of the brain and their intersystem connections in patients with post-stroke depression. 30 patients with post-stroke depression have been taken a dose of Melitor 25 mg per day for 2 months. It has been established that Melitor has a positive effect on psycho-emotional activity, improves cerebral hemodynamics, harmonizes the structure of bioelectric activity of the brain in patients with post-stroke depression. Melitor has more strong effect on cerebral hemodynamics and bioelectric activity of the brain in patients with right-sided stroke than among the patients with left-sided stroke. Melitor's multimodal influence justifies the use of the drug during the rehabilitation treatment of post-stroke patients for the improvement both functional and psycho-emotional state.
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