Estimating the functional age of the respiratory system
Abstract
The work aimed to develop a mathematical model of the functional age of the respiratory system. 95 practically healthy people aged 29 to 80 were examined. Spirograph parameters were determined on the device "Spirometer MIR Spirobank II" (manufacturer MIR S.r.l., Italy). The most informative indicators of age-related changes in the respiratory system were selected and a formula was obtained that allows to estimate the functional age of this system quite accurately. The average absolute error is 5.28 years.
References
Korkushko, O. V. The significance of respiratory, hemodynamic and tissue factors in the development of hypoxia in the elderly and senile age. Probl starenyia i dolholetyia 1998, 7, 4, 376 – 384. (in Russian)
Korkushko, O. V.; Chebotarev, D. F.; Chebotarev, N. D. Age-related changes in the respiratory system during ageing and their role in advanced broncho-pulmonary pathology. Ukrainian Pulmonology Journal 2005, 5, 35-41. (in Russian)
Belozerova, L. M. Ontogenetic method for determining biological age. Russian medical journal 2003, 4, 108-112. (in Russian)
Vovkanych, L. S. Characteristics of the methodology for determining the biological age of a person (mini-review). Zdorovyj sposib zhyttia: Lviv 2008, 28, 19 - 26. (in Ukrainian)
Ysupov, Y. B.; Nadezhkyna, E. Yu.; Fylymonova, O. S. A method for determining the biological age of a person by indicators of forced spirometry. Clinical gerontology 2014, 5, 6, 41-43. (in Russian)
Belozerova, L. M.; Odehova, T. V. Method for determining biological age by spirography. Clinical gerontology 2006, 12, 3, 53-56. (in Russian)
Korkushko, O. V.; Pysaruk, A. V.; Solovej, L. M. Functional age of the external respiration system. Probl starenyia y dolholetyia, 1992, 2, 3, 286-289.
Graham, B.; Steenbruggen, I.; Miller, M. R.; Barjaktarevic, I. Z.; Cooper, B. G. et al. Standardization of Spirometry 2019 Update. An Official American ThoracicSociety and European Respiratory Society Technical Statement. Am J Respir Crit Care Med. 2019, 200- 8, pp. 70–88. https://doi.org/10.1164/rccm.201908-1590st
Pisaruk, A. V. A simple method for correction of the systematic error in calculating biological age by the multiple regression equation. Ageing and Longevity. 2021, 2. -1, pp. 11-16. https://doi.org/10.47855/jal9020-2021-1-2