A simple method for correction of the systematic error in calculating biological age by the multiple regression equation
Abstract
There was proposed а simple method of the correction of systematic error of the equation of multiple regression while calculating biological age. The principle of this method is in the vertical transfer of points on the graph "predicted age - chronological age" on a diagonal line. At the same time, the distances from the points to the regression line are maintained. This correction eliminates the systematic error of the multiple regression equation and increases the accuracy of the biological age model.
References
Anstey, K.J.; Lord, S.R.; Smith, G.A. Measuring human functional age: a review of empirical findings. Exp Aging Res 1996, 22, pp 245–266. doi: 10.1080/03610739608254010
Aykroyd, R.G.; Lucy, D.; Pollard, A.M.; Solheim, T. Technical note: regression analysis in adult age estimation. Am J Phys Antropol 1997, 104, pp 259–265. doi: 10.1002/(SICI)1096-8644(199710)104:2<259::AID-AJPA11>3.0.CO;2-Z
Kroll, J.; Saxtrup, O. On the use of regression analysis for the estimation of human biological age. Biogerontology 2000, 1, pp 363–368. doi: 10.1023/a:1026594602252
Kumari, K.; Yadav, S. Linear regression analysis study - Journal of the practice of Cardiovascular. Sciences 2018, 4, pp 33-36. doi: 10.4103/jpcs.jpcs_8_18
Dubina, T.L.; Dyundikova, V.A.; Zhuk, E.V. Biological age and its estimation. II. Assessment of biological age of albino rats by multiple regression analysis. Exp Gerontol 1983, 18, pp 5–18. doi: 10.1016/0531-5565(83)90046-3
Dubina, T.L.; Mints, A.Y.; Zhuk, E.V. Biological age and its estimation. III. Introduction of a correction to the multiple regression model of biological age in cross-sectional and longitudinal studies. Exp Gerontol 1984, 19, pp 133–143. doi: 10.1016/0531-5565(84)90016-0
Krut’ko, V.N.; Smirnova, T.M.; Dontsov, V.I.; Borisov, S.E. Diagnosing aging: I. Problem of reliability of linear regression models of biological age. Human Physiol 2001, 27, pp 725–731.
Klemera, P.; Doubal, S. A new approach to the concept and computation of biological age. Mech Ageing Dev 2006, 127, pp 240–248. doi: 10.1016/j.mad.2005.10.004